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DOT4 Links Silencing and Cell Growth in Saccharomyces cerevisiae

Transcriptional silencing in Saccharomyces cerevisiae occurs at specific loci and is mediated by a multiprotein complex that includes Rap1p and the Sir proteins. We studied the function of a recently identified gene, DOT4, that disrupts silencing when overexpressed. DOT4 encodes an ubiquitin process...

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Auteurs principaux: Kahana, Alon, Gottschling, Daniel E.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC84633/
https://ncbi.nlm.nih.gov/pubmed/10490600
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