Methylation-Mediated Transcriptional Silencing in Euchromatin by Methyl-CpG Binding Protein MBD1 Isoforms

DNA methylation of promoter-associated CpG islands is involved in the transcriptional repression of vertebrate genes. To investigate the mechanisms underlying gene inactivation by DNA methylation, we characterized a human MBD1 protein, one of the components of MeCP1, which possesses a methyl-CpG bin...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Fujita, Naoyuki, Takebayashi, Shin-ichiro, Okumura, Katsuzumi, Kudo, Shinichi, Chiba, Tsutomu, Saya, Hideyuki, Nakao, Mitsuyoshi
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1999
Fag:	DNA Dynamics and Chromosome Structure
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84611/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454587/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.9.6415
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