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The Oncoprotein E2A-Pbx1a Collaborates with Hoxa9 To Acutely Transform Primary Bone Marrow Cells

A recurrent translocation between chromosome 1 (Pbx1) and 19 (E2A) leading to the expression of the E2A-Pbx1 fusion oncoprotein occurs in ∼5 to 10% of acute leukemias in humans. It has been proposed that some of the oncogenic potential of E2A-Pbx1 could be mediated through heterocomplex formation wi...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Thorsteinsdottir, Unnur, Krosl, Jana, Kroon, Evert, Haman, André, Hoang, Trang, Sauvageau, Guy
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1999
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84606/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454582/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.9.6355
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