Differential Roles of Akt, Rac, and Ral in R-Ras-Mediated Cellular Transformation, Adhesion, and Survival

Multiple biological functions have been ascribed to the Ras-related G protein R-Ras. These include the ability to transform NIH 3T3 fibroblasts, the promotion of cell adhesion, and the regulation of apoptotic responses in hematopoietic cells. To investigate the signaling mechanisms responsible for t...

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Autors principals: Osada, Masako, Tolkacheva, Tatyana, Li, Weiqun, Chan, Tung O., Tsichlis, Philip N., Saez, Rosana, Kimmelman, Alec C., Chan, Andrew M.-L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Cell Growth and Development
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC84604/
https://ncbi.nlm.nih.gov/pubmed/10454580
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