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Base Pairing between U3 Small Nucleolar RNA and the 5′ End of 18S rRNA Is Required for Pre-rRNA Processing

The loop of a stem structure close to the 5′ end of the 18S rRNA is complementary to the box A region of the U3 small nucleolar RNA (snoRNA). Substitution of the 18S loop nucleotides inhibited pre-rRNA cleavage at site A(1), the 5′ end of the 18S rRNA, and at site A(2), located 1.9 kb away in intern...

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Detalhes bibliográficos
Main Authors: Sharma, Kishor, Tollervey, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC84488/
https://ncbi.nlm.nih.gov/pubmed/10454548
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