Inhibition of Mitogen-Activated Kinase Signaling Sensitizes HeLa Cells to Fas Receptor-Mediated Apoptosis

The Fas receptor (FasR) is an important physiological mediator of apoptosis in various tissues and cells. However, there are also many FasR-expressing cell types that are normally resistant to apoptotic signaling through this receptor. The mitogen-activated protein kinase (MAPK) signaling cascade ha...

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Bibliographic Details
Main Authors: Holmström, Tim H., Tran, Stefanie E. F., Johnson, Victoria L., Ahn, Natalie G., Chow, Sek C., Eriksson, John E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC84476/
https://ncbi.nlm.nih.gov/pubmed/10454546
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