Histone Acetyltransferase Complexes Can Mediate Transcriptional Activation by the Major Glucocorticoid Receptor Activation Domain

Previous studies have shown that the Ada adapter proteins are important for glucocorticoid receptor (GR)-mediated gene activation in yeast. The N-terminal transactivation domain of GR, τ1, is dependent upon Ada2, Ada3, and Gcn5 for transactivation in vitro and in vivo. Using in vitro techniques, we...

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Autors principals: Wallberg, Annika E., Neely, Kristen E., Gustafsson, Jan-Åke, Workman, Jerry L., Wright, Anthony P. H., Grant, Patrick A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
Transcriptional Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC84458/
https://ncbi.nlm.nih.gov/pubmed/10454542
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