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Activity of the c-myc Replicator at an Ectopic Chromosomal Location

DNA replication starts at multiple discrete sites across the human chromosomal c-myc region, including two or more sites within 2.4 kb upstream of the c-myc gene. The corresponding 2.4-kb c-myc origin fragment confers autonomously replicating sequence (ARS) activity on plasmids, which specifically i...

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Bibliographic Details
Main Authors: Malott, Michelle, Leffak, Michael
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC84420/
https://ncbi.nlm.nih.gov/pubmed/10409757
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