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Transcription Factor TFIIH Is Required for Promoter Melting In Vivo

The Rad25 protein in yeast is a DNA helicase and a subunit of the general transcription factor TFIIH. While in vitro studies have led to the hypothesis that TFIIH helicase activity plays a role in promoter melting, in vivo tests are lacking. Using potassium permanganate, which preferentially modifie...

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Bibliographic Details
Main Authors: Guzmán, Ernesto, Lis, John T.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC84417/
https://ncbi.nlm.nih.gov/pubmed/10409754
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