The Linker Domain of Stat1 Is Required for Gamma Interferon-Driven Transcription
Upon binding of gamma interferon (IFN-γ) to its receptor, the latent transcription factor Stat1 becomes phosphorylated, dimerizes, and enters the nucleus to activate transcription. In response to IFN-α, Stat1 binds to Stat2 in a heterodimer that recruits p48, an IRF family member, to activate transc...
Zapisane w:
| Wydane w: | Mol Cell Biol |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Taylor & Francis
1999
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84353/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10373559/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.7.5106 |
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