Regulation of Nuclear Localization and Transcriptional Activity of TFII-I by Bruton’s Tyrosine Kinase

Bruton’s tyrosine kinase (Btk) is required for normal B-cell development, as defects in Btk lead to X-linked immunodeficiency (xid) in mice and X-linked agammaglobulinemia (XLA) in humans. Here we demonstrate a functional interaction between the multifunctional transcription factor TFII-I and Btk. E...

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Detalhes bibliográficos
Main Authors: Novina, Carl D., Kumar, Sanjay, Bajpai, Urmila, Cheriyath, Venugopalan, Zhang, Keming, Pillai, Shiv, Wortis, Henry H., Roy, Ananda L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC84330/
https://ncbi.nlm.nih.gov/pubmed/10373551
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