Mechanism of Protein Kinase B Activation by Cyclic AMP-Dependent Protein Kinase

Activation of protein kinase B (PKB) by growth factors and hormones has been demonstrated to proceed via phosphatidylinositol 3-kinase (PI3-kinase). In this report, we show that PKB can also be activated by PKA (cyclic AMP [cAMP]-dependent protein kinase) through a PI3-kinase-independent pathway. Al...

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Bibliografiske detaljer
Main Authors: Filippa, Nathalie, Sable, Carol L., Filloux, Chantal, Hemmings, Brian, Van Obberghen, Emmanuel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC84322/
https://ncbi.nlm.nih.gov/pubmed/10373549
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