Utilization of Splicing Elements and Polyadenylation Signal Elements in the Coupling of Polyadenylation and Last-Intron Removal

Polyadenylation (PA) is the process by which the 3′ ends of most mammalian mRNAs are formed. In nature, PA is highly coordinated, or coupled, with splicing. In mammalian systems, the most compelling mechanistic model for coupling arises from data supporting exon definition (2, 34, 37). We have exami...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Cooke, Charles, Hans, Holly, Alwine, James C.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1999
Soggetti:	Gene Expression
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84315/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10373547/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.7.4971
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