RAG-2 Promotes Heptamer Occupancy by RAG-1 in the Assembly of a V(D)J Initiation Complex

V(D)J recombination occurs at recombination signal sequences (RSSs) containing conserved heptamer and nonamer elements. RAG-1 and RAG-2 initiate recombination by cleaving DNA between heptamers and antigen receptor coding segments. RAG-1 alone contacts the nonamer but interacts weakly, if at all, wit...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Swanson, Patrick C., Desiderio, Stephen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1999
Soggetti:	DNA Dynamics and Chromosome Structure
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84178/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10207091/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.5.3674
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