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Corepressor Required for Adenovirus E1B 55,000-Molecular-Weight Protein Repression of Basal Transcription

Adenovirus E1B 55,000-molecular-weight protein (55K) binds to host cell p53, stabilizing it, greatly increasing its affinity for its cognate DNA-binding site, and converting it from a regulated activator to a constitutive repressor. Here we analyzed the mechanism of repression by the p53-E1B 55K com...

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Detalles Bibliográficos
Main Authors: Martin, Michelle E. D., Berk, Arnold J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC84133/
https://ncbi.nlm.nih.gov/pubmed/10207064
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