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Basolateral Sorting of Furin in MDCK Cells Requires a Phenylalanine-Isoleucine Motif Together with an Acidic Amino Acid Cluster

Furin is a subtilisin-related endoprotease which processes a wide range of bioactive proteins. Furin is concentrated in the trans-Golgi network (TGN), where proteolytic activation of many precursor proteins takes place. A significant fraction of furin, however, cycles among the TGN, the plasma membr...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:Mol Cell Biol
Ngā kaituhi matua: Simmen, Thomas, Nobile, Massimo, Bonifacino, Juan S., Hunziker, Walter
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Taylor & Francis 1999
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84107/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10082580/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.4.3136
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