Subtle Mutagenesis by Ends-in Recombination in Malaria Parasites

The recent advent of gene-targeting techniques in malaria (Plasmodium) parasites provides the means for introducing subtle mutations into their genome. Here, we used the TRAP gene of Plasmodium berghei as a target to test whether an ends-in strategy, i.e., targeting plasmids of the insertion type, m...

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Bibliografiske detaljer
Main Authors: Nunes, Alvaro, Thathy, Vandana, Bruderer, Thomas, Sultan, Ali A., Nussenzweig, Ruth S., Ménard, Robert
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
DNA Dynamics and Chromosome Structure
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC84083/
https://ncbi.nlm.nih.gov/pubmed/10082556
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