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Recruitment of TATA-Binding Protein–TAF(I) Complex SL1 to the Human Ribosomal DNA Promoter Is Mediated by the Carboxy-Terminal Activation Domain of Upstream Binding Factor (UBF) and Is Regulated by UBF Phosphorylation

Human rRNA synthesis by RNA polymerase I requires at least two auxiliary factors, upstream binding factor (UBF) and SL1. UBF is a DNA binding protein with multiple HMG domains that binds directly to the CORE and UCE elements of the ribosomal DNA promoter. The carboxy-terminal region of UBF is necess...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tuan, JoAnn C., Zhai, Weiguo, Comai, Lucio
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC84080/
https://ncbi.nlm.nih.gov/pubmed/10082553
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