The c-fos Proto-Oncogene Is a Target for Transactivation by the p53 Tumor Suppressor

The p53 tumor suppressor gene is mutated in over 50% of human cancers, resulting in inactivation of the wild-type (wt) p53 protein. The most notable biochemical feature of p53 is its ability to act as a sequence-specific transcriptional activator. Through use of the suppression subtractive hybridiza...

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Main Authors: Elkeles, Adi, Juven-Gershon, Tamar, Israeli, David, Wilder, Sylvia, Zalcenstein, Amir, Oren, Moshe
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC84052/
https://ncbi.nlm.nih.gov/pubmed/10082525
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