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Ku-Dependent Nonhomologous DNA End Joining in Xenopus Egg Extracts

An extract from activated Xenopus eggs joins both matching and nonmatching ends of exogenous linear DNA substrates with high efficiency and fidelity (P. Pfeiffer and W. Vielmetter, Nucleic Acids Res. 16:907–924, 1988). In mammalian cells, such nonhomologous end joining (NHEJ) is known to require the...

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Bibliografske podrobnosti
Glavni avtor: Labhart, Paul
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC84051/
https://ncbi.nlm.nih.gov/pubmed/10082524
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