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All-trans-Retinoic Acid Inhibits Jun N-Terminal Kinase by Increasing Dual-Specificity Phosphatase Activity

Jun N-terminal kinases (JNKs) are serine-threonine kinases that play a critical role in the regulation of cell growth and differentiation. We previously observed that JNK activity is suppressed by all-trans-retinoic acid (t-RA), a ligand for retinoic acid nuclear receptors (RARs), in normal human br...

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Hlavní autoři: Lee, Ho-Young, Sueoka, Naoko, Hong, Waun-Ki, Mangelsdorf, David J., Claret, Francois X., Kurie, Jonathan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC83990/
https://ncbi.nlm.nih.gov/pubmed/10022884
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