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Alterations in the Conserved SL1 trans-Spliced Leader of Caenorhabditis elegans Demonstrate Flexibility in Length and Sequence Requirements In Vivo

Approximately 70% of mRNAs in Caenorhabditis elegans are trans spliced to conserved 21- to 23-nucleotide leader RNAs. While the function of SL1, the major C. elegans trans-spliced leader, is unknown, SL1 RNA, which contains this leader, is essential for embryogenesis. Efforts to characterize in vivo...

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Autori principali: Ferguson, Kimberly C., Rothman, Joel H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC83982/
https://ncbi.nlm.nih.gov/pubmed/10022876
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