Ral-Specific Guanine Nucleotide Exchange Factor Activity Opposes Other Ras Effectors in PC12 Cells by Inhibiting Neurite Outgrowth

Ras proteins can activate at least three classes of downstream target proteins: Raf kinases, phosphatidylinositol-3 phosphate (PI3) kinase, and Ral-specific guanine nucleotide exchange factors (Ral-GEFs). In NIH 3T3 cells, activated Ral-GEFs contribute to Ras-induced cell proliferation and oncogenic...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Goi, Takanori, Rusanescu, Gabriel, Urano, Takeshi, Feig, Larry A.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1999
Fag:	Cell Growth and Development
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC83966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10022860/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.3.1731
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