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The Nuclease Activity of Mre11 Is Required for Meiosis but Not for Mating Type Switching, End Joining, or Telomere Maintenance

The Saccharomyces cerevisiae MRE11 gene is required for the repair of ionizing radiation-induced DNA damage and for the initiation of meiotic recombination. Sequence analysis has revealed homology between Mre11 and SbcD, the catalytic subunit of an Escherichia coli enzyme with endo- and exonuclease...

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Библиографические подробности
Главные авторы: Moreau, Sylvie, Ferguson, John R., Symington, Lorraine S.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1999
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC83913/
https://ncbi.nlm.nih.gov/pubmed/9858579
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