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The Repertoire of Fos and Jun Proteins Expressed during the G(1) Phase of the Cell Cycle Is Determined by the Duration of Mitogen-Activated Protein Kinase Activation

In Rat-1 fibroblasts nonmitogenic doses of lysophosphatidic acid (LPA) stimulate a transient activation of mitogen-activated protein kinase (MAPK), whereas mitogenic doses elicit a sustained response. This sustained phase of MAPK activation regulates cell fate decisions such as proliferation or diff...

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Detalhes bibliográficos
Main Authors: Cook, Simon J., Aziz, Natasha, McMahon, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC83891/
https://ncbi.nlm.nih.gov/pubmed/9858557
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