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Alternative Splicing Results in Differential Expression, Activity, and Localization of the Two Forms of Arginyl-tRNA-Protein Transferase, a Component of the N-End Rule Pathway

The N-end rule relates the in vivo half-life of a protein to the identity of its N-terminal residue. The underlying ubiquitin-dependent proteolytic system, called the N-end rule pathway, is organized hierarchically: N-terminal aspartate and glutamate (and also cysteine in metazoans) are secondary de...

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Udgivet i:Mol Cell Biol
Principais autores: Kwon, Yong Tae, Kashina, Anna S., Varshavsky, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1999
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC83877/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9858543/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.1.182
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