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miRNome and Functional Network Analysis of PGRMC1 Regulated miRNA Target Genes Identify Pathways and Biological Functions Associated With Triple Negative Breast Cancer

BACKGROUND: Increased expression of the progesterone receptor membrane component 1, a heme and progesterone binding protein, is frequently found in triple negative breast cancer tissue. The basis for the expression of PGRMC1 and its regulation on cellular signaling mechanisms remain largely unknown....

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Détails bibliographiques
Publié dans:Front Oncol
Auteurs principaux: Pedroza, Diego A., Ramirez, Matthew, Rajamanickam, Venkatesh, Subramani, Ramadevi, Margolis, Victoria, Gurbuz, Tugba, Estrada, Adriana, Lakshmanaswamy, Rajkumar
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8327780/
https://ncbi.nlm.nih.gov/pubmed/34350123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.710337
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