DUX4r, ZNF384r and PAX5-P80R mutated B-cell precursor acute lymphoblastic leukemia frequently undergo monocytic switch

Recently, we described B-cell precursor acute lymphoblastic leukemia (BCP-ALL) subtype with an early switch to the monocytic lineage and the loss of the B-cell immunophenotype, including CD19 expression. Thus far, the genetic background has remained unknown. Among 726 children consecutively diagnose...

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Veröffentlicht in:Haematologica
Hauptverfasser: Novakova, Michaela, Zaliova, Marketa, Fiser, Karel, Vakrmanova, Barbora, Slamova, Lucie, Musilova, Alena, Brüggemann, Monika, Ritgen, Matthias, Fronkova, Eva, Kalina, Tomas, Stary, Jan, Winkowska, Lucie, Svec, Peter, Kolenova, Alexandra, Stuchly, Jan, Zuna, Jan, Trka, Jan, Hrusak, Ondrej, Mejstrikova, Ester
Format: Artigo
Sprache:Inglês
Veröffentlicht: Fondazione Ferrata Storti 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8327733/
https://ncbi.nlm.nih.gov/pubmed/32646889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2020.250423
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