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PSPC1 is a new contextual determinant of aberrant subcellular translocation of oncogenes in tumor progression

Dysregulation of nucleocytoplasmic shuttling is commonly observed in cancers and emerging as a cancer hallmark for the development of anticancer therapeutic strategies. Despite its severe adverse effects, selinexor, a selective first-in-class inhibitor of the common nuclear export receptor XPO1, was...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Main Authors: Lang, Yaw-Dong, Jou, Yuh-Shan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8327449/
https://ncbi.nlm.nih.gov/pubmed/34340703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-021-00753-3
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