Cell-intrinsic effects of TorsinA(ΔE) disrupt dopamine release in a mouse model of TOR1A dystonia

TOR1A-associated dystonia, otherwise known as DYT1 dystonia, is an inherited dystonia caused by a three base-pair deletion in the TOR1A gene (TOR1AΔE). Although the mechanisms underlying the dystonic movements are largely unknown, abnormalities in striatal dopamine and acetylcholine neurotransmissio...

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Bibliografiska uppgifter
I publikationen:Neurobiol Dis
Huvudupphovsmän: Downs, Anthony M., Fan, Xueliang, Kadakia, Radhika F., Donsante, Yuping, Jinnah, H.A., Hess, Ellen J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2021
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8327367/
https://ncbi.nlm.nih.gov/pubmed/33894367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2021.105369
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