Glucagon-Like Peptide-1 Analog Exendin-4 Ameliorates Cocaine-Mediated Behavior by Inhibiting Toll-Like Receptor 4 Signaling in Mice

Exendin-4 (Ex4), a long-lasting glucagon-like peptide-1 analog, was reported to exert favourable actions on inhibiting cocaine-associated rewarding and reinforcing effects of drug in animal models of addiction. However, the therapeutic potential of different dose of GLP-1 receptor agonist Ex4 in dif...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Zhu, Changliang, Tao, Hong, Rong, Shikuo, Xiao, Lifei, Li, Xinxiao, Jiang, Shucai, Guo, Baorui, Wang, Lei, Ding, Jiangwei, Gao, Caibing, Chang, Haigang, Sun, Tao, Wang, Feng
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8327264/
https://ncbi.nlm.nih.gov/pubmed/34349653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.694476
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