Metformin improves FOXP3 mRNA expression through suppression of interferon gamma levels in pristane-induced murine models of lupus

Background:  A recent study has indicated the potential of metformin therapy for lupus in animal models, but there has been no study evaluating the effect on pristane-induced lupus. This study aims to evaluate the effect of intraperitoneal versus oral metformin on interferon (IFN)-γ levels and FOXP3...

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Veröffentlicht in:F1000Res
Hauptverfasser: Sumantri, Stevent, Hatta, Mochammad, Natzir, Rosdiana, Rasyid, Haerani, Rengganis, Iris, Massi, Muhammad Nasrum, Islam, Andi Asadul, Lawrence, Gatot, Patellongi, Ilhamjaya, Benyamin, Andi Fachruddin
Format: Artigo
Sprache:Inglês
Veröffentlicht: F1000 Research Limited 2021
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8327221/
https://ncbi.nlm.nih.gov/pubmed/34386197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.23471.2
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