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Intestinal Metabolites Influence Macrophage Phagocytosis and Clearance of Bacterial Infection

The metabolite-rich environment that is the intestinal lumen contains metabolic by-products deriving from microbial fermentation and host cell metabolism, with resident macrophages being constantly exposed to this metabolic flux. Succinate, lactate and itaconate are three metabolites secreted by pri...

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Detalles Bibliográficos
Publicado en:Front Cell Infect Microbiol
Main Authors: O’Callaghan, Amy A., Dempsey, Elaine, Iyer, Namrata, Stiegeler, Sarah, Mercurio, Kevin, Corr, Sinéad C.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8327167/
https://ncbi.nlm.nih.gov/pubmed/34350128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.622491
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