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Protocol for tissue clearing and 3D analysis of dopamine neurons in the developing mouse midbrain

Advances in tissue clearing enable analysis of complex migratory patterns of developing neurons in whole intact tissue. Here, we implemented a modified version of 3DISCO to study migration of midbrain dopamine (DA) neurons. We provide a detailed protocol starting from whole-brain immunostaining, tis...

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Bibliografiske detaljer
Udgivet i:STAR Protoc
Main Authors: Adolfs, Youri, Raj, Divya D.A., Brignani, Sara, Pasterkamp, R. Jeroen
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8326876/
https://ncbi.nlm.nih.gov/pubmed/34377993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100669
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