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Natural Course of Activated Phosphoinositide 3-Kinase Delta Syndrome in Childhood and Adolescence
Activated phosphoinositide 3-kinase delta syndrome (APDS), caused by mutations in PI3Kδ catalytic p110δ (PIK3CD) or regulatory p85α (PIK3R1) subunits, is a primary immunodeficiency affecting both humoral and cellular immunity, which shares some phenotypic similarities with hyper-IgM syndromes and co...
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| Publié dans: | Front Pediatr |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8326455/ https://ncbi.nlm.nih.gov/pubmed/34350147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fped.2021.697706 |
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