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Prolonged norovirus infections correlate to quasispecies evolution resulting in structural changes of surface-exposed epitopes
In this study, we analyzed norovirus (NoV) evolution in sequential samples of six chronically infected patients. The capsid gene was amplified from stool samples, and deep sequencing was performed. The role of amino acid flexibility in structural changes and ligand binding was studied with molecular...
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| 出版年: | iScience |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8324856/ https://ncbi.nlm.nih.gov/pubmed/34355146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102802 |
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