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Cost-effective circadian mechanism: rhythmic degradation of circadian proteins spontaneously emerges without rhythmic post-translational regulation

Circadian protein oscillations are maintained by the lifelong repetition of protein production and degradation in daily balance. It comes at the cost of ever-replayed, futile protein synthesis each day. This biosynthetic cost with a given oscillatory protein profile is relievable by a rhythmic, not...

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Podrobná bibliografie
Vydáno v:iScience
Hlavní autoři: Lim, Roktaek, Chae, Junghun, Somers, David E., Ghim, Cheol-Min, Kim, Pan-Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8324817/
https://ncbi.nlm.nih.gov/pubmed/34355141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102726
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