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Acetate sensing by GPR43 alarms neutrophils and protects from severe sepsis

Bacterial sepsis is a major cause of mortality resulting from inadequate immune responses to systemic infection. Effective immunomodulatory approaches are urgently needed but it has remained elusive, which targets might be suitable for intervention. Increased expression of the G-protein-coupled rece...

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Dettagli Bibliografici
Pubblicato in:Commun Biol
Autori principali: Schlatterer, Katja, Beck, Christian, Schoppmeier, Ulrich, Peschel, Andreas, Kretschmer, Dorothee
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8324776/
https://ncbi.nlm.nih.gov/pubmed/34330996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02427-0
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