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Acetate sensing by GPR43 alarms neutrophils and protects from severe sepsis

Bacterial sepsis is a major cause of mortality resulting from inadequate immune responses to systemic infection. Effective immunomodulatory approaches are urgently needed but it has remained elusive, which targets might be suitable for intervention. Increased expression of the G-protein-coupled rece...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Schlatterer, Katja, Beck, Christian, Schoppmeier, Ulrich, Peschel, Andreas, Kretschmer, Dorothee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8324776/
https://ncbi.nlm.nih.gov/pubmed/34330996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02427-0
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