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Selective recruitment of γδ T cells by a bispecific antibody for the treatment of acute myeloid leukemia

Despite significant progress over the last few decades in the treatment of acute myeloid leukemia (AML), there still remains a major unmet medical need for this disease. Immunotherapy approaches for redirecting pan CD3(+) T cells to target leukemia blasts have shown limited efficacy in clinical tria...

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Опубликовано в: :Leukemia
Главные авторы: Ganesan, Rajkumar, Chennupati, Vijaykumar, Ramachandran, Balaji, Hansen, Michael Riis, Singh, Sanjaya, Grewal, Iqbal S.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8324575/
https://ncbi.nlm.nih.gov/pubmed/33526858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-021-01122-7
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