Impacts of Ecology, Parasite Antigenic Variation, and Human Genetics on RTS,S/AS01e Malaria Vaccine Efficacy

PURPOSE OF REVIEW: Global malaria elimination has little chance of success without an effective vaccine. The first malaria vaccine, RTS,S/AS01e, demonstrated moderate efficacy against clinical malaria in phase III trials and is undergoing large-scale effectiveness trials in Africa. Importantly, the...

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Vydáno v:Curr Epidemiol Rep
Hlavní autoři: Bell, Griffin J., Agnandji, Selidji Todagbe, Asante, Kwaku Poku, Ghansah, Anita, Kamthunzi, Portia, Emch, Michael, Bailey, Jeffrey A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2021
Témata:
Infectious Disease Epidemiology (M Yotebieng, Section Editor)
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8324449/
https://ncbi.nlm.nih.gov/pubmed/34367877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40471-021-00271-8
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