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Binding of Dipeptides to Fatty Acid Membranes Explains Their Colocalization in Protocells, but Does Not Select for Them Relative to Unjoined Amino Acids

Dipeptides, which consist of two amino acids joined by a peptide bond, have been shown to have catalytic function. This observation leads to fundamental questions relevant to the origins of life. How could peptides have become co-localized with the first protocells? Which structural features would h...

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Pubblicato in:J Phys Chem B
Autori principali: Xue, Mengjun, Black, Roy A., Cohen, Zachary R., Roehrich, Adrienne, Drobny, Gary P., Keller, Sarah L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8323988/
https://ncbi.nlm.nih.gov/pubmed/34283913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.1c01485
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