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Profiling of microRNA targets using activity-based protein profiling: linking enzyme activity to microRNA-185 function

MicroRNAs (miRNAs) act as cellular signal transducers through repression of protein translation. Elucidating targets using bioinformatics and traditional quantitation methods is often insufficient to uncover global miRNA function. Herein, alteration of protein function caused by microRNA-185 (miR-18...

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Publicado en:Cell Chem Biol
Autores principales: Filip, Roxana, Desrochers, Geneviève F., Lefebvre, David M., Reed, Alex, Singaravelu, Ragunath, Cravatt, Benjamin F., Pezacki, John Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8323987/
https://ncbi.nlm.nih.gov/pubmed/33450181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2020.12.009
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