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Exploiting DNA repair pathways for tumor sensitization, mitigation of resistance, and normal tissue protection in radiotherapy
More than half of cancer patients are treated with radiotherapy, which kills tumor cells by directly and indirectly inducing DNA damage, including cytotoxic DNA double-strand breaks (DSBs). Tumor cells respond to these threats by activating a complex signaling network termed the DNA damage response...
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| Publié dans: | Cancer Drug Resist |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
OAE Publishing Inc.
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8323830/ https://ncbi.nlm.nih.gov/pubmed/34337349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20517/cdr.2020.89 |
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