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pH-Responsive STING-Activating DNA Nanovaccines for Cancer Immunotherapy

Cyclic dinucleotides (CDNs), such as c-di-GMP (CDG), are agonists for stimulator of interferon genes (STING) and are promising for cancer immunotherapy. Yet, the therapeutic efficacy of CDNs has been limited by poor delivery and biostability. Here, STING-activating DNA nanovaccines (STING-NVs) are d...

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Detalhes bibliográficos
Publicado no:Adv Ther (Weinh)
Main Authors: Zhang, Yu, Shen, Tingting, Zhou, Shurong, Wang, Weinan, Lin, Shuibin, Zhu, Guizhi
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8323737/
https://ncbi.nlm.nih.gov/pubmed/34337143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adtp.202000083
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