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Combination of PARP inhibitor and temozolomide to suppress chordoma progression
Chordoma, a malignant bone cancer, is highly resistant to conventional therapeutic approaches; this greatly limits radio- and chemotherapeutic options and disease management. In the present study, we investigated three patient-derived chordoma cell lines to elucidate the molecular mechanism of resis...
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| Publicado no: | J Mol Med (Berl) |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8323588/ https://ncbi.nlm.nih.gov/pubmed/31201471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-019-01802-z |
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