A Personalized Therapeutics Approach Using an In Silico Drosophila Patient Model Reveals Optimal Chemo- and Targeted Therapy Combinations for Colorectal Cancer

In silico models of biomolecular regulation in cancer, annotated with patient-specific gene expression data, can aid in the development of novel personalized cancer therapeutic strategies. Drosophila melanogaster is a well-established animal model that is increasingly being employed to evaluate such...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Gondal, Mahnoor Naseer, Butt, Rida Nasir, Shah, Osama Shiraz, Sultan, Muhammad Umer, Mustafa, Ghulam, Nasir, Zainab, Hussain, Risham, Khawar, Huma, Qazi, Romena, Tariq, Muhammad, Faisal, Amir, Chaudhary, Safee Ullah
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8323493/
https://ncbi.nlm.nih.gov/pubmed/34336681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.692592
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