DNA Methylation-Based Interferon Scores Associate With Sub-Phenotypes in Primary Sjögren’s Syndrome

Primary Sjögren’s syndrome (pSS) is an autoimmune inflammatory disease with profound clinical heterogeneity, where excessive activation of the type I interferon (IFN) system is considered one of the key mechanisms in disease pathogenesis. Here we present a DNA methylation-based IFN system activation...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Imgenberg-Kreuz, Juliana, Sandling, Johanna K., Norheim, Katrine Brække, Johnsen, Svein Joar Auglænd, Omdal, Roald, Syvänen, Ann-Christine, Svenungsson, Elisabet, Rönnblom, Lars, Eloranta, Maija-Leena, Nordmark, Gunnel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8322981/
https://ncbi.nlm.nih.gov/pubmed/34335613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.702037
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