Red blood cells contain enzymatically active GPx4 whose abundance anticorrelates with hemolysis during blood bank storage

The antioxidant function of the phospholipid hydroperoxide glutathione peroxidase (GPx4) is vital for the homeostasis of many cell types, from neoplastic cells to normal erythroid precursors. However, some functional proteins in erythroid precursors are lost during the development of red blood cells...

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Bibliografische gegevens
Gepubliceerd in:Redox Biol
Hoofdauteurs: Stolwijk, Jeffrey M., Stefely, Jonathan A., Veling, Mike T., van ‘t Erve, Thomas J., Wagner, Brett A., Raife, Thomas J., Buettner, Garry R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2021
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8322435/
https://ncbi.nlm.nih.gov/pubmed/34298465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.102073
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