CFTR is a negative regulator of γδ T cell IFN-γ production and antitumor immunity

CFTR, a chloride channel and ion channel regulator studied mostly in epithelial cells, has been reported to participate in immune regulation and likely affect the risk of cancer development. However, little is known about the effects of CFTR on the differentiation and function of γδ T cells. In this...

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Udgivet i:Cell Mol Immunol
Main Authors: Duan, Yuanyuan, Li, Guangqiang, Xu, Miaomiao, Qi, Xiaofei, Deng, Mingxia, Lin, Xuejia, Lei, Zhiwei, Hu, Yi, Jia, Zhenghu, Yang, Quanli, Cao, Guangchao, Liu, Zonghua, Wen, Qiong, Li, Zhenhua, Tang, Jie, Zhang, Wei Kevin, Huang, Pingbo, Zheng, Limin, Flavell, Richard A., Hao, Jianlei, Yin, Zhinan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8322328/
https://ncbi.nlm.nih.gov/pubmed/32669666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-020-0499-3
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