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Local and downstream actions of proximal tubule angiotensin II signaling on Na(+) transporters in the mouse nephron

The renal nephron consists of a series of distinct cell types that function in concert to maintain fluid and electrolyte balance and blood pressure. The renin-angiotensin system (RAS) is central to Na(+) and volume balance. We aimed to determine how loss of angiotensin II signaling in the proximal t...

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Publicat a:Am J Physiol Renal Physiol
Autors principals: Nelson, Jonathan W., McDonough, Alicia A., Xiang, Zhidan, Ralph, Donna L., Robertson, Joshua A., Giani, Jorge F., Bernstein, Kenneth E., Gurley, Susan B.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8321806/
https://ncbi.nlm.nih.gov/pubmed/34056928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00014.2021
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